Acute Myelocythæmia Associated with Osteosclerosis
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چکیده
منابع مشابه
Acute Myeloid Leukemia with Isolated Trisomy 19 Associated with Diffuse Myelofibrosis and Osteosclerosis
Primary myelofibrosis (PMF), per WHO criteria, is a clonal myeloproliferative neoplasm that usually presents with a proliferation of granulocytic and megakaryocytic lineages with an associated fibrous deposition and extramedullary hematopoiesis. The bone marrow histologic findings of this disorder are typically characterized by the presence of myeloid metaplasia with an associated reactive fibr...
متن کاملStimulation of osteoprotegerin production is responsible for osteosclerosis in mice overexpressing TPO.
Myelofibrosis and osteosclerosis are prominent features arising in mice overexpressing thrombopoietin (TPO). The pivotal role of transforming growth factor beta 1 (TGF-beta 1) in the pathogenesis of myelofibrosis has been documented, but the mechanisms mediating osteosclerosis remain unclear. Here, we used mice deficient in osteoprotegerin (OPG), a secreted inhibitor of bone resorption, to dete...
متن کاملIntramedullary osteosclerosis: An incidental sclerotic lesion in a trauma patient
Intramedullary osteosclerosis, a rare entity, is usually diagnosed after the exclusion of more sinister etiologies. It typically affects the lower extremity and is more common in females. While the lesion may be discovered incidentally during imaging, presenting symptoms may include pain in the affected bone that is exacerbated with physical activity. Laboratory values are normal, and the lesio...
متن کاملPrevalence of Idiopathic Osteosclerosis on Cone Beam Computed Tomography Images
Objectives: This study was performed to investigate the prevalence of idiopathic osteosclerosis on cone beam computed tomography (CBCT) images of patients. Methods: In this descriptive, cross-sectional study, 240 CBCT scans of patients (125 women, 115 men) referred to a private oral and maxillofacial radiology clinic in Tehran in 2013 were selected and evaluated. Presence of idiopathic osteosc...
متن کاملA comparative analysis of magnetic resonance imaging and high-resolution peripheral quantitative computed tomography of the hand for the detection of erosion repair in rheumatoid arthritis.
OBJECTIVES To investigate whether MRI allows the detection of osteosclerosis as a sign of repair of bone erosions compared with high-resolution peripheral quantitative computed tomography (HR-pQCT) as a reference and whether the presence of osteosclerosis on HR-pQCT is linked to synovitis and osteitis on MRI. METHODS A total of 103 RA patients underwent HR-pQCT and MRI of the dominant hand. T...
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عنوان ژورنال:
دوره 31 شماره
صفحات -
تاریخ انتشار 2017